CYCLOBENZAPRINE®
Cyclobenzaprine® is a drug used as a muscle relaxer. Cyclobenzaprine is the generic form of Flexeril. Cyclobenzaprine® taken by people with fibromyalgia seem to have less pain and fatigue, fewer painful trigger points, and improved sleep.
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Cyclobenzaprine®
Cyclobenzaprine HCl is a white, crystalline tricyclic amine salt with the empirical formula C20H21N·HCl and a molecular weight of 311.9. It has a melting point of 217°C, and a pKa of 8.47 at 25° C. It is freely soluble in water and alcohol, sparingly soluble in isopropanol, and insoluble in hydrocarbon solvents. If aqueous solutions are made alkaline, the free base separates. Cyclobenzaprine HCl is designated chemically as 3-(5H-dibenzo[a,d] cyclohepten-5-ylidene)-N, N-dimethyl-1-propanamine hydrochloride. Cyclobenzaprine HCl is
supplied as 10 mg tablets for oral administration. Inactive Ingredients: Hydroxypropyl cellulose, hydroxypropyl methylcellulose, iron oxide, lactose, magnesium stearate, starch, and titanium dioxide.
Cyclobenzaprine Important Note
The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
Cyclobenzaprine Uses
Cyclobenzaprine relaxes muscles and alleviates pain and discomfort associated with strains, sprains, spasms or other muscle injuries.
How to Use Cyclobenzaprine
May be taken with food if stomach upset occurs. Take Cyclobenzaprine as directed. Do not increase your dose or take it more often than prescribed.
Cyclobenzaprine Side Effects
May cause stomach upset, heartburn, constipation, headache, dizziness or drowsiness or dry mouth the first few days as your body adjusts to the medication. If these symptoms persist or become severe, notify your doctor. Inform your doctor if you develop: muscle stiffness, skin rash, itching, rapid heart rate, swelling of the face, difficulty urinating. When rising quickly from a sitting or lying position, dizziness or lightheadedness may occur. Change positions slowly and use caution on stairs. Avoid activities requiring alertness if dizziness or drowsiness occurs. If you notice other effects not listed above, contact your doctor or pharmacist.
Cyclobenzaprine Precautions
Before taking this drug, tell your doctor if you have: glaucoma, an overactive thyroid gland, heart disease, difficulty urinating, any allergies. Inform your doctor if you are pregnant or breast-feeding before taking this drug.
Cyclobenzaprine Drug Interactions
Tell your doctor of any over-the-counter or prescription medications you take, especially of: cimetidine, antidepressants, sedatives, tranquilizers, sleeping pills, narcotic pain medication (e.g., codeine), anti-allergy drugs, drugs used for asthma, cough-and-cold medicines. Alcohol adds to the dizziness and drowsiness caused by cyclobenzaprine. Limit alcohol intake. Do not start or stop any medicine without doctor or pharmacist approval.
Cyclobenzaprine Overdose
If overdose is suspected, contact your local poison control center or emergency room straight away. Symptoms of overdose may include drowsiness, fast or irregular heartbeat, enlarged pupils, seizures, and loss of consciousness.
Cyclobenzaprine Notes
Do not use for longer than 3 weeks unless specifically instructed to do so. Cyclobenzaprine provides temporary relief and must be used in addition to rest, physical therapy and other measures. Do not allow anyone else to take Cyclobenzaprine.
Missed Dose
If you miss a dose, take as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.
Storage
Store at room temperature away from sunlight and moisture.
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